百济神州
Principal Pathologist, Pharmacology
岗位职责
We are seeking a pathologist to join the in vivo pharmacology team to support programs in preclinical and clinical development stages. The individual will bring pathology expertise with hands-on approaches to guide preclinical decisions and assist with decision making as programs move to clinical trials. The individual will help to optimize the histology and toxicology approaches, design studies and move the programs forward using high-quality tissue-based assays and data analysis. The individual will work cross-functionally with the project teams across a broad spectrum of portfolios including but not limited to Tumor Biology, Immuno-oncology and Non-oncology programs. Responsibility Build, organize and operate a translational pathology laboratory Being a vital member of the team to develop and optimize pathology methods for drug R&D. This includes, but not limited to, techniques used for molecular pathology, histology, investigative pathology/toxicology Drive high quality data analysis relevant to pathology and manage data generated both internally and externally Build a state-of-the-art pathology technology platform, including but not limited to, methods of IHC, IF and ISH to support characterization of established and novel targets. Guide pathology and imaging decision making with teams as drug candidates approach clinical stages Provide expert guidance on pathology and other tissue-based assays for cross functional research and development teams as needed Contribute to the implementation of pathology laboratory information & data management system Comply with regulated laboratory standards for pathology and IHC documentation and reporting standards Contribute to IND/NDA/CTA filing as the pharmacology/toxicology section author
任职要求
Position will be hired based on level of experience Master or Ph.D. degree in molecular biology, cancer biology, pathology or related fields Proven record of relevant experience and expertise in toxicology pathology or translational pathology work in drug discovery and/or development settings Hands-on experience with a wide array of anatomic pathology laboratory platforms (e.g., histology, IHC/ISH/IF/multiplexing, light/fluorescent/confocal microscopy, digital pathology image analysis) across fresh frozen and paraffin-embedded formats Experienced in assay development and optimization, and trouble-shooting of IHC/ISH/multiplexing assays and image analysis Previous exposure to IND/CTA filing is a plus Self-starter attitude, excellent interpersonal skills and comfortable in a fast pace biotech environment 百济神州全球胜任力 当我们通过以下十二项全球胜任力,展现出 "患者为先"、"无界协作"、"锐意创新 "和 "追求卓越 "的价值观时,我们就能帮助全世界更多患者获得更多负担得起的药品。 ●团队协作 ●提供并征求坦诚及可行的反馈 ●自我认知 ●兼容并蓄 ●积极主动 ●开拓精神 ●持续学习 ●拥抱变化 ●结果导向 ●分析性思维/数据分析 ●卓越财务 ●清晰沟通 BeOne Global Competencies When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. ●Fosters Teamwork ●Provides and Solicits Honest and Actionable Feedback ●Self-Awareness ●Acts Inclusively ●Demonstrates Initiative ●Entrepreneurial Mindset ●Continuous Learning ●Embraces Change ●Results-Oriented ●Analytical Thinking/Data Analysis ●Financial Excellence ●Communicates with Clarity 求职者隐私申明: 百济神州致力于尊重和保护您的个人信息权利,并承诺依据合法、正当、必要和诚信的原则处理您的个人信息(包括个人敏感信息 )。 由于百济神州在全球范围内开展业务,我们可能需要基于人力资源管理等合理业务目的而将您的个人信息发送和/或存储在位于您所在国家以外其他国家(例如:美国)的服务器和数据库中,详情参见百济神州《求职者隐私政策》(百济神州官网 - 隐私政策 - 求职者隐私政策)。 如您主动向我们提供您的简历信息或其他个人信息,则视为您已经充分理解并确认接受百济神州《求职者隐私政策》内容。如您对此有任何疑问的,请勿提交简历信息或其他个人信息。 BeOne is committed to respect and protect your personal information rights, and will process your personal information, including your sensitive personal information, based on the principles of legality, legitimacy, necessity, and integrity. Due to the reasonable business need for human resource management as a result of BeOne’s global operation, your personal information may be transferred and/ or stored in a server/database located in a third country (e.g., the United States) other than your own country. For further details, please refer to BeOne Job Applicant Privacy Policy (BeOne official website - Privacy Policy - Job Applicant Privacy Policy). If you voluntarily provide your resume or other personal information to us, it is deemed as you have thoroughly acknowledged and accepted BeOne Job Applicant Privacy Policy. If you have any concern, please DO NOT submit your resume or any other personal information.
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