Met ID 代谢物鉴定(J10383)

1. Responsible for sample preparation and sample running with HR-MS.

负责样品制备和利用HR-MS进行样品分析。

2. Responsible for data QC, protocol, report preparation & verification.

负责数据QC，方案，报告整理和核对。

3. Develop LC-UV-MS and/or LC/radio detection/MS methods for detection, identification

and semi-quantitative analysis of metabolites。

开发LC-UV-MS和/或LC/radio detection/MS方法，用于检测、鉴定和半定量分析代谢

物。

4. Acquire knowledge on metabolite detection, characterization experiments in liver

microsomes, S9 fraction, hepatocytes, plasma, urine, bile and tissues.

掌握肝微粒体、S9组分、肝细胞、血浆、尿液、胆汁和组织中进行代谢物检测、表

征的知识。

5. Learn study related guidelines, SOPs, protocols and technical reports.

学习项目相关的法规、SOPs、方案和技术报告。

6. Assist in instrument maintenance to support the project need.

协助维护仪器设备，以满足项目的检测需求。

7. Complying with EH&S policy. Maintain tidy in their workplace; Use personal protective

equipment properly.

遵守安全守则。维持工作区域的清洁。试验中合理的使用个人防护设备。

Bachelor or Master’s degree in drug metabolism, pharmacokinetics, organic chemistry,

analytical chemistry and other related areas. knowledge in drug metabolism, enzymology

and/or structural elucidation of small molecules and large molecules. Hands-on experience is

plus in the use and maintenance of LC-high-resolution mass spectrometry for detection and

structurally characterization of small molecules and large molecules in biological samples. Good

English oral and writing skills.

药物代谢、药代动力学、有机化学、分析化学等相关领域学士或硕士毕业生。药物代谢、

酶学和/或小分子和大分子结构阐明方面的知识。具有使用和维护液相色谱-高分辨质谱的

实际经验，用于生物样品中小分子和大分子检测和结构表征是加分项。良好的英语口语和

写作技巧。