(Senior) Director, Discovery Biology (Oncology)

BeOne is growing rapidly and creating exceptional opportunities for outstanding research leaders who want to make a meaningful difference in oncology. We are seeking passionate, innovative, and highly collaborative scientific leaders who are driven to transform cancer care and advance the next generation of breakthrough therapies. If you are inspired by the opportunity to shape the future of oncology and work alongside a world-class R&D team, we invite you to join us on this exciting journey. Role Overview As a key scientific leader within our Discovery Biology team, you will play a central role in advancing cutting-edge oncology drug discovery programs from target concept through preclinical development. You will lead target discovery, evaluation, and validation efforts while helping to build a differentiated and future-focused pipeline spanning small molecules, induced proximity approaches, PROTACs, novel immuno-oncology concepts, ADCs, mRNA/siRNA therapies, and other emerging modalities. In this highly visible role, you will partner across multidisciplinary teams to drive first-in-class therapeutic innovation, shape scientific strategy, and accelerate promising programs toward clinical development. Key Accountabilities Lead target and disease biology investigations, generate compelling new target proposals, and drive robust target evaluation and validation. Provide scientific and strategic leadership for preclinical project teams in a cross-functional, matrixed environment to advance clinical candidate nominations and IND-enabling studies. Champion scientific excellence and innovation by integrating emerging technologies, including AI-enabled approaches, to accelerate discovery and transform research productivity. Oversee day-to-day team operations while mentoring and developing scientists to build a high-performing, collaborative, and growth-oriented organization. Shape department-level talent strategies, including recruitment, retention, capability building, and long-term career development. Drive alignment across diverse stakeholders and lead cross-functional initiatives in a complex organizational environment. Communicate scientific insights with clarity and influence through high-quality written and verbal presentations to project teams, senior leadership, and key governance meetings. Foster external scientific visibility and impact through publications in leading journals and presentations at major internal and external conferences. Candidate Profile PhD and/or MD in cancer biology or a related field, with 10+ years of relevant experience in pharma or biotech drug discovery; deep expertise in solid tumors is strongly

. Strong record of independent scientific thinking, innovation, and creative problem-solving, demonstrated through original research and influential publications. Proven success in target identification and validation, scientific team leadership, and advancing programs to clinical candidate nomination and IND submission. Experience in translational science is a plus. Demonstrated ability to lead effectively across disciplines, partnering with Medicinal Chemistry, Bioengineering, DMPK, Toxicology, Translational Science, and Regulatory functions to drive high-quality decisions at key governance milestones. Established track record of scientific excellence reflected in high-impact publications and/or intellectual property generation. Why BeOne At BeOne, we empower exceptional scientists to do bold, meaningful work that has the potential to change patients’ lives. You will have the opportunity to shape breakthrough therapies, influence scientific strategy, and grow your career in an ambitious, collaborative, and globally connected R&D environment. 百济神州全球胜任力 当我们通过以下十二项全球胜任力，展现出 "患者为先"、"无界协作"、"锐意创新 "和 "追求卓越 "的价值观时，我们就能帮助全世界更多患者获得更多负担得起的药品。 ●团队协作 ●提供并征求坦诚及可行的反馈 ●自我认知 ●兼容并蓄 ●积极主动 ●开拓精神 ●持续学习 ●拥抱变化 ●结果导向 ●分析性思维/数据分析 ●卓越财务 ●清晰沟通 BeOne Global Competencies When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. ●Fosters Teamwork ●Provides and Solicits Honest and Actionable Feedback ●Self-Awareness ●Acts Inclusively ●Demonstrates Initiative ●Entrepreneurial Mindset ●Continuous Learning ●Embraces Change ●Results-Oriented ●Analytical Thinking/Data Analysis ●Financial Excellence ●Communicates with Clarity 求职者隐私申明： 百济神州致力于尊重和保护您的个人信息权利，并承诺依据合法、正当、必要和诚信的原则处理您的个人信息（包括个人敏感信息 ）。 由于百济神州在全球范围内开展业务，我们可能需要基于人力资源管理等合理业务目的而将您的个人信息发送和/或存储在位于您所在国家以外其他国家（例如：美国）的服务器和数据库中，详情参见百济神州《求职者隐私政策》（百济神州官网 - 隐私政策 - 求职者隐私政策）。 如您主动向我们提供您的简历信息或其他个人信息，则视为您已经充分理解并确认接受百济神州《求职者隐私政策》内容。如您对此有任何疑问的，请勿提交简历信息或其他个人信息。 BeOne is committed to respect and protect your personal information rights, and will process your personal information, including your sensitive personal information, based on the principles of legality, legitimacy, necessity, and integrity. Due to the reasonable business need for human resource management as a result of BeOne’s global operation, your personal information may be transferred and/ or stored in a server/database located in a third country (e.g., the United States) other than your own country. For further details, please refer to BeOne Job Applicant Privacy Policy (BeOne official website - Privacy Policy - Job Applicant Privacy Policy). If you voluntarily provide your resume or other personal information to us, it is deemed as you have thoroughly acknowledged and accepted BeOne Job Applicant Privacy Policy. If you have any concern, please DO NOT submit your resume or any other personal information.