药明生物
Intact mass scientist-CD
岗位职责
SUMMARY AND KEY ACCOUNTIBILITIES: WuXiBiologics is seeking a qualified candidate to fill a Scientist level position within its CRO Services department in Chengdu. This position is within the Protein Analytical Chemistry group and will work collaboratively in cross-functional teams on a range of programs from research protein generation. The candidate will work in a highly collaborative environment to utilize skills in partnership with internal purification team and other functional groups. Use LC-MS technique, especially intact mass, to support research protein production and a broad range of biologic projects. Use comprehensive analytical methods to support in-depth characterization of biologics, including but not limited to intact mass, caliper, SEC_HPLC and glycan analysis. Support technical transfer, training and trouble-shooting of protein engineering and production for R&D purposes, including but not limited to protein engineering for therapeutic proteins, humanization and affinity maturation of antibodies and developability assessment.
任职要求
You love analytics and are passionate about using data to drive key business decisions. You love learning new technological skills and working through collaboration. You will provide expertise in the field of in-depth protein analysis as it pertains to biologics characterization and other novel therapy related work with possibility to support other modalities, as opportunities arise. Direct experience in the analytical characterization for biologics and/or glycoproteins using intact protein analysis, including post-translational modification analysis, and/or glycosylation elucidation. In-depth knowledge and hands-on experience in different types of analytical separation techniques and data processing analyses with focus on mass spectrometry applications. Knowledge of other analytical techniques such as chromatography (HPLC/UPLC), electrophoresis (CE-SDS, icIEF), biophysical methods. Broad expertise and familiarity with protein and antibody production, drug discovery and early CMC development Strong problem-solving and troubleshooting skills, capabilities in experimental design and execution, ability to work on multiple projects simultaneously, as well ability to work independently and collaborate cross-functionally EDUCATION (Indicate the mini. requirement & preferred discipline): MS degree/BS with at least 5 years industry experience Major:Analytical chemistry/ Biochemistry/Biophysics/Protein Chemistry, or related field OTHER SKILLS, ABILITIES & EXPERIENCE: Good communication skills required Strong team-working spirit
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